Terpenes are organic compounds that occur in plants, fruits, trees, and cannabis and are responsible for their flavors and fragrances.

Terpenes have other functions besides producing aromas and flavors, however. They contribute to an important biological phenomenon known as the “entourage effect.”

The entourage effect describes the synergy that exists between terpenes and cannabinoids as well as lesser metabolites and phytochemicals. In the entourage effect, terpenes facilitate the work of cannabis molecules in the brain and the body. As such, they play an important role on the cannabis stage. (Terpenoids are not usually present in CBD-only products.)

Different kinds of molecules in cannabis plants bind to cells and receptors in the human body. Phytocannabinoid molecules, flavonoids, and terpenes are some of the substances that interact with a person’s brain and body to impact one’s senses and experiences.

Terpenes contribute to plants’ signature compositions and contain properties that benefit the human body. Dr. Ethan Russon, in the September 2011 issue of the British Journal of Pharmacology, explored these benefits.

The therapeutic effects of terpenoids and cannabinoids that Dr. Russo lists in his article include improved cortical functioning and higher blood flow rates. Other possible benefits of terpenoids and cannabinoids include assistance in the treatment and management of depression, anxiety, pain, inflammation, cancer, epilepsy, addiction, and infections.

Terpenoids and cannabinoids kill pathogens that attack the respiratory system, including the bacterium MRSA, a deadly organism that resists antibiotics and has killed thousands of people in the United States.



Wilson Botanics uses a unique blend of hemp-derived terpenes infused back into our original CBD isolate hemp oil. This process produces a THC free, CBD oil along with terpenes to help get more benefit out of the CBD and closer to the often sought after “entourage effect”.

Terpenes in our CBD oil blend may include, but not limited to:



In the natural world, pinene is the most commonly occurring variety of terpene. Its components may be helpful for the management of pain, anxiety, and inflammation.

The medical values of pinene were first researched forty years ago. The study of pinene’s efficacies has continued systematically, especially in the area of its anti-viral and anti-inflammatory properties.

Pinene facilitates the movement of oxygen into cells, which makes it a bronchodilator. It acts against the body’s mechanisms that cause sedation, which results in a person being more alert, clear-minded, and focused.



The terpene Beta-Caryophyllene is historically significant as being one of the first-discovered non-cannabinoids that interacts with and activates cannabinoid receptors. “CB2” receptors, which are the receptors most typically activated by CBD, serve a function in relieving pain. When Beta-Caryophyllene activates the body’s CB2 receptors, it facilitates the pain-relieving properties of CBD and THC.

Beta-Caryophyllene has a clove-like fragrance with sweet, spicy, and woody notes. It is a sesquiterpene, unique among terpenes because of its large size and structure. These characteristics enable Beta-Caryophyllene to activate several of the body’s receptors, not just CB2 receptors.

Beta-Caryophyllene regulates neuroinflammation and thermal hyperalgesia, giving it analgesic properties. It prevents lipid oxidation and scavenging radicals, so as such is also an effective antioxidant.

Other benefits of Beta-Caryophyllene include its anti-inflammatory and gastro-protective properties.



The terpene Limonene helps to fight bacteria and reduce inflammation. It also combats stress and anxiety, fights free radicals, boosts energy, and helps the body absorb cannabinoids.

Unsurprisingly, Limonene smells and tastes like citrus; in fact, the peels of citrus fruits contain high amounts of this terpene. Consumers are familiar with Limonene as an active ingredient in household cleaners, food, medicine, and perfume. Historically, this terpene has been used as a home remedy for acne and athlete’s foot.

Limonene also functions as an antidepressant, showing results comparable to some commonly prescribed medications. As an anti-inflammatory, it helps to thwart the early stages of inflammation episodes.

Limonene has been suggested as a possible combative agent for prostate, breast, and pancreatic cancer.



Lavender and other flowers and spices contain the terpene Linalool. Its fragrance can be woody, sweet, floral, and citrusy. Plants that contain Linalool have been used through the ages for their aromas that help reduce stress levels.

The subject of numerous scientific studies, Linalool boasts the unusual ability of relieving pain through its interaction with opioidergic and cholinergic systems. Among terpenes, this is a unique pathway to pain relief.

Linalool can act as an anticonvulsant. It relieves anxiety. It has been used as a relaxation agent for thousands of years.

Terpenes are still very much under research. Their properties, interactions, and benefits have yet to be unequivocally proven.



Terpenes in our CBD Pain Cream may include, but not limited to: